A trusted partner at nearly three million customer locations, Ecolab is the global leader in water, hygiene and infection prevention solutions and services. With annual sales of €12 billion and more than 50,000 associates, Ecolab delivers comprehensive solutions, data-driven insights and personalised service to advance food safety, maintain clean and safe environments, optimise water and energy use, and improve operational efficiencies and sustainability for customers in the food, healthcare, hospitality, Life Sciences and industrial markets in more than 170 countries around the world.

Ecolab is committed to providing exceptional service, total plant solutions, and unsurpassed industry expertise to help you achieve your business goals. Our breadth of resources and integrated business model ensure consistency across your operations.

Purolite - Praesto® Jetted A50

Products for Protein A Chromatography

Products for Protein A Chromatography

Praesto Jetted A50 is a high-performance agarose-based Protein A resin that delivers exceptional performance in terms of capacity, pressure flow and lifetime. Designed to meet the mAb processing demands of tomorrow, today, the combination of a highly cross-linked Praesto agarose base matrix with the NGL-ImpactTM A ligand from Repligen® provides increased capacity and excellent alkaline stability, reducing your bioburden risk and improving your process efficiencies from the same manufacturing footprint.

Purolite - Praesto® Jetted A50 HipH

Products for Protein A Chromatography

Products for Protein A Chromatography

The unique properties of Praesto Jetted A50 HipH address challenges in eluting pH-sensitive mAbs and Fc-containing proteins, which can become unstable at pH levels typically used for elution with other Protein A resins (3 – 3.5). This resin provides alkaline stability, a capacity of 60 g/L for polyclonal human IgG and elution up to pH 5. This creates a wider operational window for your Protein A step, facilitating rapid process development and processing of all Fc-containing molecules by:
  • Enabling the use of a classic antibody purification platform
  • Retaining the unique specificity of Protein A for high recovery and excellent productivity
  • Minimizing impact on facility fit with comparable elution volumes and buffer usage
  • Lowering levels of post-Protein A contaminants, reducing polishing challenges and driving process robustness

Purolite - Praesto® SP45 / SP65 /SP90

Products for CEX Chromatography

Products for Protein A Chromatography

Agarose Highly Cross-Linked Strong Cation Exchanger, 45 μm particle size Principal Applications: 
  • Protein purification (20-500 kDa)
  • MAb Purification
Advantages:
  • Excellent dynamic binding capacities for high productivity and scalability
  • Outstanding pressure/flow performance
  • High resolution/selectivity
  • Excellent chemical and physical stability
  • Secure, validated supply and regulatory support
  • Enabling the use of a classic antibody purification platform
  • Retaining the unique specificity of Protein A for high recovery and excellent productivity
  • Minimizing impact on facility fit with comparable elution volumes and buffer usage
  • Lowering levels of post-Protein A contaminants, reducing polishing challenges and driving process robustness

Purolite - Praesto® SP35

Products for CEX Chromatography

Products for Protein A Chromatography

Agarose Highly Cross-Linked Strong Cation Exchanger, Uniform Particle Size, 35 μm Principal Applications:
  • Protein purification (20-500 kDa)
  • MAb Purification
Advantages:
  • Manufactured using the patented Jetting technique
  • Uniform particle size
  • Enhanced productivity
  • High dynamic binding capacity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support

Purolite - Praesto® Jetted Q35

Products for AEX Chromatography

Products for Protein A Chromatography

Agarose Highly Cross-Linked Strong Anion Exchanger, Uniform Particle Size, 35 µm Principal Applications:
  • Protein purification (20-500 kDa)
  • MAb Purification
Advantages:
  • Manufactured using the patented Jetting technique
  • Uniform particle size
  • High capacity, enhanced productivity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support

Purolite - Praesto® Q45 / Q65 / Q90

Products for AEX Chromatography

Products for Protein A Chromatography

Agarose Highly Cross-Linked Strong Anion Exchanger, Uniform Particle Size, 35 µm Principal Applications:
  • Protein purification (20-500 kDa)
  • MAb Purification
Advantages:
  • Manufactured using the patented Jetting technique
  • Uniform particle size
  • High capacity, enhanced productivity
  • Enhanced pressure/flow performance
  • Manufactured with reduced environmental impact
  • Secure, validated supply and regulatory support
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