NXT Valve

The NXTvalve SBV (Split Butterfly Valve) is purpose-engineered to deliver safe, contained, and highly efficient powder transfer in mission-critical environments such as pharmaceutical, biopharmaceutical, and chemical manufacturing. Developed with stringent regulatory and operational demands in mind, the NXTvalve ensures that both potent and non-potent powders are transferred with maximum safety and minimal risk of cross-contamination. Designed for versatility, the NXTvalve is ideal for handling Active Pharmaceutical Ingredients (APIs), excipients, and granulated materials, offering robust performance across all major powder-handling operations. These include dispensing, filling, container loading and unloading, and reactor or vessel charging, where it acts as a reliable containment interface between transfer points.
With manual operation mode, the NXTvalve integrates seamlessly into existing process lines or new installations, supporting everything from R&D scale to full-scale commercial production. Its modular design ensures easy maintenance, repeatable performance, and long-term durability, making it a preferred solution for operators and engineers focused on process integrity, product quality, and worker safety.

NXTvalve Operation Sequence

• Passive body
• Product
• Active/Passive disk
• Active body
• IBC/Powder bag

How the NXTvalve SBV Works

The core of the NXTvalve SBV (Split Butterfly Valve) system is its innovative two-part design, featuring an Active and Passive disc half. These two halves are engineered to mate precisely along their axis of rotation, forming a robust metal-to-metal seal at the outer edge of the discs. This unique sealing mechanism ensures high containment integrity and particle-tight closure, even under demanding conditions.

Application of NXTvalve

• Dispensing
• Vessel Charging
• Filtration
• Centrifugation
• Drying
• Sampling
• Granulation
• Blendiing
• Milling
• Sieving
• Compression
• Filling
• Coating

NXTValve Performance

After powder transfer using the NXTValve SBV, a small amount of residue may remain on the mating surfaces, typically along the disc edge where the valve closes. This is due to powder adhering during closure and may vary based on the properties, such as particle size, moisture, or electrostatic charge. While not a system fault, it’s essential to address it as part of good GMP practice. Operators should inspect and clean both the Active and Passive units immediately after undocking using lint-free or compliant materials. This maintains hygiene, prevents cross-contamination, and supports compliance. For high-containment or sticky powders, PharmNXT Biotech offers advanced options such as anti-stick coatings, improved disc designs, and cleaning accessories to reduce residue and
enhance performance.

NXTValve SIP Passive:

The NXTValve SIP Passive (Active Cleaning Cap) connects to the Active valve to enable cleaning or sterilization within a sealed environment. An O-ring seal ensures a liquid- and gas-tight interface.

Available in two versions:

SIP Passive Cap for Active: With a tri-clamp connection for steam supply, SIP, or decontamination media. It can also serve as a process vent or drain when installed inverted.

SIP Passive Cleaning Cap for Active: Includes a fixed spray ball for WIP/CIP/SIP applications and can be used inverted for in-place cleaning and drainage.

The cylindrically shaped design of SIP Passive supports condensate drainage during SIP and drying cycles. The unit can be pressure rated for recirculation, flood, or high-pressure wash cycles.